Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment (2024)

References

  1. Noda, M. et al. Expression of functional sodium channels from cloned cDNA. Nature 322, 826–828 (1986)

    Article ADS CAS PubMed Google Scholar

  2. Ramsey, I. S., Moran, M. M., Chong, J. A. & Clapham, D. E. A voltage-gated proton-selective channel lacking the pore domain. Nature 440, 1213–1216 (2006)

    Article ADS CAS PubMed PubMed Central Google Scholar

  3. Sasaki, M., Takagi, M. & Okamura, Y. A voltage sensor-domain protein is a voltage-gated proton channel. Science 312, 589–592 (2006)

    Article ADS CAS PubMed Google Scholar

  4. Murata, Y., Iwasaki, H., Sasaki, M., Inaba, K. & Okamura, Y. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435, 1239–1243 (2005)

    Article ADS CAS PubMed Google Scholar

  5. Armstrong, C. M. & Bezanilla, F. Charge movement associated with the opening and closing of the activation gates of the Na+ channels. J. Gen. Physiol. 63, 533–552 (1974)

    Article CAS PubMed PubMed Central Google Scholar

  6. Jiang, Y. et al. X-ray structure of a voltage-dependent K+ channel. Nature 423, 33–41 (2003)

    Article ADS CAS PubMed Google Scholar

  7. Long, S. B., Campbell, E. B. & MacKinnon, R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309, 897–903 (2005)

    Article ADS CAS PubMed Google Scholar

  8. Lee, S. Y., Lee, A., Chen, J. & MacKinnon, R. Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane. Proc. Natl Acad. Sci. USA 102, 15441–15446 (2005)

    Article ADS CAS PubMed PubMed Central Google Scholar

  9. Stuhmer, W. et al. Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain. EMBO J. 8, 3235–3244 (1989)

    Article CAS PubMed PubMed Central Google Scholar

  10. Frech, G. C., VanDongen, A. M., Schuster, G., Brown, A. M. & Joho, R. H. A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature 340, 642–645 (1989)

    Article ADS CAS PubMed Google Scholar

  11. Alabi, A. A., Bahamonde, M. I., Jung, H. J. Kim, J. I. & Swartz, K. J. Portability of paddle motif function and pharmacology in voltage sensors. Nature doi: 10.1038/nature06266 (this issue)

  12. Kamb, A., Iverson, L. E. & Tanouye, M. A. Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Cell 50, 405–413 (1987)

    Article CAS PubMed Google Scholar

  13. Tempel, B. L., Papazian, D. M., Schwarz, T. L., Jan, L. Y. & Jan, Y. N. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila . Science 237, 770–775 (1987)

    Article ADS CAS PubMed Google Scholar

  14. Pongs, O. et al. Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila . EMBO J. 7, 1087–1096 (1988)

    Article CAS PubMed PubMed Central Google Scholar

  15. Zhou, Y., Morais-Cabral, J. H., Kaufman, A. & MacKinnon, R. Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution. Nature 414, 43–48 (2001)

    Article ADS CAS PubMed Google Scholar

  16. Nishida, M., Cadene, M., Chait, B. T. & MacKinnon, R. Crystal of a Kir3.1–prokaryotic Kir channel chimera. EMBO J. 26, 4005–4015 (2007)

    Article CAS PubMed PubMed Central Google Scholar

  17. Jiang, Y., Ruta, V., Chen, J., Lee, A. & MacKinnon, R. The principle of gating charge movement in a voltage-dependent K+ channel. Nature 423, 42–48 (2003)

    Article ADS CAS PubMed Google Scholar

  18. Long, S. B., Campbell, E. B. & MacKinnon, R. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 309, 903–908 (2005)

    Article ADS CAS PubMed Google Scholar

  19. Schmidt, D., Jiang, Q. X. & MacKinnon, R. Phospholipids and the origin of cationic gating charges in voltage sensors. Nature 444, 775–779 (2006)

    Article ADS CAS PubMed Google Scholar

  20. Lu, Z., Klem, A. M. & Ramu, Y. Coupling between voltage sensors and activation gate in voltage-gated K+ channels. J. Gen. Physiol. 120, 663–676 (2002)

    Article CAS PubMed PubMed Central Google Scholar

  21. Sukhareva, M., Hackos, D. H. & Swartz, K. J. Constitutive activation of the Shaker Kv channel. J. Gen. Physiol. 122, 541–556 (2003)

    Article CAS PubMed PubMed Central Google Scholar

  22. Jiang, Y. et al. The open pore conformation of potassium channels. Nature 417, 523–526 (2002)

    Article ADS CAS PubMed Google Scholar

  23. Swartz, K. J. & MacKinnon, R. Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels. Neuron 18, 675–682 (1997)

    Article CAS PubMed Google Scholar

  24. Laskowski, R. A. MacArthur M. W., Moss, D. S. & Thornton, J. M. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26, 283–291 (1993)

    Article CAS Google Scholar

  25. Branden, C. & Tooze, J. Introduction to Protein Structure page 15 (Garland Publishing Inc., New York, 1999)

    Google Scholar

  26. Zagotta, W. N., Hoshi, T., Dittman, J. & Aldrich, R. W. Shaker potassium channel gating. II: transitions in the activation pathway. J. Gen. Physiol. 103, 279–319 (1994)

    Article CAS PubMed Google Scholar

  27. Schoppa, N. E., McCormack, K., Tanouye, M. A. & Sigworth, F. J. The size of gating charge in wild-type and mutant Shaker potassium channels. Science 255, 1712–1715 (1992)

    Article ADS CAS PubMed Google Scholar

  28. Aggarwal, S. K. & MacKinnon, R. Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron 16, 1169–1177 (1996)

    Article CAS PubMed Google Scholar

  29. Seoh, S. A., Sigg, D., Papazian, D. M. & Bezanilla, F. Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron 16, 1159–1167 (1996)

    Article CAS PubMed Google Scholar

  30. Islas, L. D. & Sigworth, F. J. Voltage sensitivity and gating charge in Shaker and Shab family potassium channels. J. Gen. Physiol. 114, 723–742 (1999)

    Article CAS PubMed PubMed Central Google Scholar

  31. Larsson, H. P., Baker, O. S., Dhillon, D. S. & Isacoff, E. Y. Transmembrane movement of the Shaker K+ channel S4. Neuron 16, 387–397 (1996)

    Article CAS PubMed Google Scholar

  32. Starace, D. M. & Bezanilla, F. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature 427, 548–553 (2004)

    Article ADS CAS PubMed Google Scholar

  33. Starace, D. M. & Bezanilla, F. Histidine scanning mutagenesis of basic residues of the S4 segment of the shaker K+ channel. J. Gen. Physiol. 117, 469–490 (2001)

    Article CAS PubMed PubMed Central Google Scholar

  34. Ruta, V., Chen, J. & MacKinnon, R. Calibrated measurement of gating-charge arginine displacement in the KvAP voltage-dependent K+ channel. Cell 123, 463–475 (2005)

    Article CAS PubMed Google Scholar

  35. King, G. I. & White, S. H. Determining bilayer hydrocarbon thickness from neutron diffraction measurements using strip-function models. Biophys. J. 49, 1047–1054 (1986)

    Article ADS CAS PubMed PubMed Central Google Scholar

  36. Burley, S. K. & Petsko, G. A. Amino–aromatic interactions in proteins. FEBS Lett. 203, 139–143 (1986)

    Article CAS PubMed Google Scholar

  37. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A47, 110–119 (1991)

    Article CAS Google Scholar

  38. Brunger, A. T. et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D54, 905–921 (1998)

    CAS Google Scholar

  39. Ruta, V., Jiang, Y., Lee, A., Chen, J. & MacKinnon, R. Functional analysis of an archeabacterial voltage-dependent K+ channel. Nature 422, 180–185 (2003)

    Article ADS CAS PubMed Google Scholar

  40. Miller, C. Ion Channel Reconstitution (Plenum, New York, 1986)

    Book Google Scholar

  41. Miller, C., Moczydlowski, E., Latorre, R. & Phillips, M. Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle. Nature 313, 316–318 (1985)

    Article ADS CAS PubMed Google Scholar

  42. Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307–326 (1997)

    Article CAS PubMed Google Scholar

  43. Collaborative Computational Project. The CCP4 suite: programs for X-ray crystallography. Acta Crystallogr. D 50, 760–763 (1994)

  44. Vagin, A. & Teplyakov, A. An approach to multi-copy search in molecular replacement. Acta Crystallogr. D 56, 1622–1624 (2000)

    Article CAS PubMed Google Scholar

  45. Heginbotham, L., LeMasurier, M., Kolmakova-Partensky, L. & Miller, C. Single streptomyces lividans K+ channels: functional asymmetries and sidedness of proton activation. J. Gen. Physiol. 114, 551–560 (1999)

    Article CAS PubMed PubMed Central Google Scholar

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment (2024)

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